Timi 2 flow7/14/2023 ![]() Restoration of microcirculatory patency after myocardial infarction: results of current coronary interventional strategies and techniques. ![]() Fernandes MR, Fish RD, Canales J, Aliota J, Silva GV, Perin EC, Elayda MA, Wilson JM.Myocardial perfusion patterns related to thrombolysis in myocardial infarction perfusion grades after coronary angioplasty in patients with acute anterior wall myocardial infarction. Ito H, Okamura A, Iwakura K, Masuyama T, Hori M, Takiuchi S, Negoro S, Nakatsuchi Y, Taniyama Y, Higashino Y, Fujii K, Minamino T.Incidence and outcomes of no-reflow phenomenon during percutaneous coronary intervention among patients with acute myocardial infarction. Harrison RW, Aggarwal A, Ou FS, Klein LW, Rumsfeld JS, Roe MT, Wang TY, Registry ACoCNCD.Clinical characteristics and outcome of patients with early (4 h) presentation treated by primary coronary angioplasty or thrombolytic therapy for acute myocardial infarction. Zijlstra F, Patel A, Jones M, Grines CL, Ellis S, Garcia E, Grinfeld L, Gibbons RJ, Ribeiro EE, Ribichini F, Granger C, Akhras F, Weaver WD, Simes RJ.The Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes (GUSTO IIb) Angioplasty Substudy Investigators. A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator for acute myocardial infarction.The Primary Angioplasty in Myocardial Infarction Study Group. A comparison of immediate angioplasty with thrombolytic therapy for acute myocardial infarction. Grines CL, Browne KF, Marco J, Rothbaum D, Stone GW, O'Keefe J, Overlie P, Donohue B, Chelliah N, Timmis GC.Angiographic study of mutant tissue-type plasminogen activator versus urokinase for acute myocardial infarction. Nagao K, Satou K, Watanabe I, Arima K, Yamashita M, Ooiwa K, Kanmatsuse K.Thrombolytic therapy for acute myocardial infarction. The effects of tissue plasminogen activator, streptokinase, or both on coronary-artery patency, ventricular function, and survival after acute myocardial infarction.Clinical significance of post-procedural TIMI flow in patients with cardiogenic shock undergoing primary percutaneous coronary intervention. Mehta RH, Ou FS, Peterson ED, Shaw RE, Hillegass WB, Rumsfeld JS, Roe MT, Investigators ACoC-NCDR.TIMI 3 flow after primary angioplasty is an important predictor for outcome in patients with acute myocardial infarction. Kammler J, Kypta A, Hofmann R, Kerschner K, Grund M, Sihorsch K, Steinwender C, Lambert T, Helml W, Leisch F.Received: NovemAccepted: ApPrepublished online: ApPublished: MaShow citation Keywords: STE myocardial infarction, PCI, TIMI 3 flow, time-delay, mortality, microcirculation Conclusion: Time delay to reperfusion is significantly related to 1-year mortality of patients with STEMI/BBB-MI and complete restoration of epicardial blood flow in culprit vessel after PCI. Other significant variables associated with mortality in multivariate regression analysis were: left ventricle ejection fraction 65 years ( P 2 ( P <0.001), female gender ( P = 0.019), and creatinine clearance < 30 mL/min ( P < 0.001). Multiple logistic regression analysis identified time delay ≥ 9 h as significantly related to 1-year mortality of patients with STEMI/BBB-MI and post-PCI TIMI 3 flow (OR 1.958, P = 0.026). Median TD in patients who survived was 3.92 h (iqr 5.43), in patients who died 6.0 h (iqr 11.42), P = 0.004. Results: A total of 83 patients (13.07%) with postprocedural TIMI 3 flow after PCI had died at 1-year follow-up. Mortality of patients was evaluated in relation to the time from symptom onset to reperfusion. Methods: Observational study based on a retrospective analysis of population of 635 consecutive patients with STEMI/BBB-MI and post-PCI TIMI 3 flow from January 2009 to December 2011 (mean age 63 years, 69.6% males). We hypothesized that the outcome of patients with STEMI/bundle branch block (BBB)-myocardial infarction and post-PCI TIMI 3 flow is related to the time to reperfusion. Nevertheless, even with complete restoration of epicardial blood flow in culprit vessel (postprocedural Thrombolysis in Myocardial Infarction (TIMI) flow grade 3), myocardial perfusion at tissue level may be insufficient. 2016, 160(1):118-124 | DOI: 10.5507/bp.2015.015 Mortality in patients with TIMI 3 flow after PCI in relation to time delay to reperfusion Teodora Vichova, Marek Maly, Jaroslav Ulman, Zuzana Motovska 3 rd Department of Internal Medicine - Cardiology, 3 rd Faculty Medicine, Charles University in Prague and University Hospital Kralovske Vinohrady, Prague, Czech Republicīackground: Percutaneous coronary intervention (PCI) performed within 12 h from symptom onset enables complete blood flow restoration in infarct-related artery in 90% of patients. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub.
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